Item Type | Name |
Academic Article
|
Whole-genome analysis informs breast cancer response to aromatase inhibition.
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Concept
|
Nuclear Magnetic Resonance, Biomolecular
|
Concept
|
Bone Resorption
|
Concept
|
Humans
|
Concept
|
Bleomycin
|
Concept
|
Cattle
|
Concept
|
Benchmarking
|
Concept
|
Child
|
Concept
|
beta Catenin
|
Concept
|
Primates
|
Concept
|
Coleoptera
|
Concept
|
Biological Transport
|
Concept
|
Escherichia coli
|
Concept
|
Workflow
|
Concept
|
Rabbits
|
Concept
|
Computer Systems
|
Concept
|
Bone Marrow
|
Concept
|
Biosensing Techniques
|
Concept
|
Genes, Bacterial
|
Concept
|
Kava
|
Concept
|
Protein Binding
|
Concept
|
I-kappa B Kinase
|
Concept
|
Tumor Burden
|
Concept
|
Staphylococcus aureus
|
Concept
|
Anti-Bacterial Agents
|
Concept
|
Brain Neoplasms
|
Concept
|
DNA-Binding Proteins
|
Concept
|
Motor Activity
|
Concept
|
Blood-Brain Barrier
|
Concept
|
NF-kappa B
|
Concept
|
Chloride-Bicarbonate Antiporters
|
Concept
|
Software
|
Concept
|
Fasting
|
Concept
|
Animals, Newborn
|
Concept
|
Brain
|
Concept
|
Aged, 80 and over
|
Concept
|
Heterozygote
|
Concept
|
Rats, Inbred Strains
|
Concept
|
Fatty Acid-Binding Proteins
|
Concept
|
Fetal Blood
|
Concept
|
Yeasts
|
Concept
|
Computer Simulation
|
Concept
|
Moths
|
Concept
|
Lymphoma, B-Cell
|
Concept
|
Bicarbonates
|
Concept
|
Proto-Oncogene Proteins B-raf
|
Concept
|
Biomarkers, Tumor
|
Concept
|
Baculoviridae
|
Concept
|
Biological Assay
|
Concept
|
Protein Biosynthesis
|
Concept
|
Molecular Biology
|
Concept
|
Mice, Knockout
|
Concept
|
Statistics as Topic
|
Concept
|
Herpesvirus 1, Human
|
Concept
|
Animals
|
Concept
|
Double-Blind Method
|
Concept
|
Chronic Disease
|
Concept
|
Aged
|
Concept
|
Bone Marrow Transplantation
|
Concept
|
GTP-Binding Proteins
|
Concept
|
HIV-1
|
Concept
|
Cricetinae
|
Concept
|
Mice, Inbred NOD
|
Concept
|
Mice, Inbred A
|
Concept
|
Mice, Inbred AKR
|
Concept
|
ATP-Binding Cassette Transporters
|
Concept
|
Models, Animal
|
Concept
|
Bacterial Proteins
|
Concept
|
Human T-lymphotropic virus 1
|
Concept
|
Binding Sites
|
Concept
|
Biological Availability
|
Concept
|
Bone and Bones
|
Concept
|
Mice, Inbred BALB C
|
Concept
|
Plant Roots
|
Concept
|
Lipid Bilayers
|
Concept
|
Tissue Donors
|
Concept
|
Biological Clocks
|
Concept
|
Barium
|
Concept
|
Anthozoa
|
Concept
|
rho GTP-Binding Proteins
|
Concept
|
Whole Body Imaging
|
Concept
|
Receptor, Interferon alpha-beta
|
Concept
|
Drug Evaluation
|
Concept
|
Bone Density Conservation Agents
|
Concept
|
Bone Remodeling
|
Concept
|
Biomimetic Materials
|
Concept
|
Adolescent
|
Concept
|
Blotting, Western
|
Concept
|
Rheology
|
Concept
|
Mice, Nude
|
Concept
|
Adenoviridae
|
Concept
|
Mice, SCID
|
Concept
|
Bromodeoxyuridine
|
Concept
|
Mice, Congenic
|
Concept
|
Mice, Inbred Strains
|
Concept
|
DNA Breaks, Double-Stranded
|
Concept
|
Tacrolimus Binding Proteins
|
Concept
|
Myositis, Inclusion Body
|
Concept
|
Rats
|
Concept
|
beta 2-Microglobulin
|
Concept
|
I-kappa B Proteins
|
Concept
|
Benzeneacetamides
|
Concept
|
Vitreous Body
|
Concept
|
Photorhabdus
|
Concept
|
Image Processing, Computer-Assisted
|
Concept
|
bcl-X Protein
|
Concept
|
Benzamides
|
Concept
|
Biochemistry
|
Concept
|
Bacterial Infections
|
Concept
|
Breast Neoplasms
|
Concept
|
B-Lymphocytes
|
Concept
|
Specific Pathogen-Free Organisms
|
Concept
|
Bone Neoplasms
|
Concept
|
Bacterial Physiological Phenomena
|
Concept
|
Cricetulus
|
Concept
|
Rats, Inbred BN
|
Concept
|
Integrin beta3
|
Concept
|
Biomarkers
|
Concept
|
Biopsy
|
Concept
|
Bone Density
|
Concept
|
Child, Preschool
|
Concept
|
Mice
|
Concept
|
Image Enhancement
|
Concept
|
Models, Biological
|
Concept
|
Olfactory Bulb
|
Concept
|
Biological Transport, Active
|
Concept
|
Middle Aged
|
Concept
|
Mice, Neurologic Mutants
|
Concept
|
Plasmodium falciparum
|
Concept
|
beta-Transducin Repeat-Containing Proteins
|
Concept
|
Buffers
|
Concept
|
Rats, Sprague-Dawley
|
Concept
|
Bacteria
|
Concept
|
Bayes Theorem
|
Concept
|
Mice, Inbred DBA
|
Concept
|
Genetic Vectors
|
Concept
|
Young Adult
|
Concept
|
Whole-Body Irradiation
|
Concept
|
Benzylamines
|
Concept
|
Blood Proteins
|
Concept
|
Carcinoma, Ductal, Breast
|
Concept
|
Base Sequence
|
Concept
|
Gene Expression Regulation, Bacterial
|
Concept
|
Amyloid beta-Peptides
|
Concept
|
Salmonella typhimurium
|
Concept
|
Mice, Mutant Strains
|
Concept
|
Radiation Chimera
|
Concept
|
RNA-Binding Proteins
|
Concept
|
Simplexvirus
|
Concept
|
Mice, Inbred ICR
|
Concept
|
Adult
|
Concept
|
Mice, Inbred C57BL
|
Concept
|
Blood Flow Velocity
|
Concept
|
Boronic Acids
|
Concept
|
Blood Platelets
|
Concept
|
Mice, Transgenic
|
Concept
|
Bumetanide
|
Concept
|
Animals, Genetically Modified
|
Concept
|
Chickens
|
Concept
|
Benzothiazoles
|
Concept
|
rap1 GTP-Binding Proteins
|
Concept
|
Bile Ducts
|
Academic Article
|
Hedgehog signaling inhibition blocks growth of resistant tumors through effects on tumor microenvironment.
|
Academic Article
|
Uptake of the cation hexakis(2-methoxyisobutylisonitrile)-technetium-99m by human carcinoma cell lines in vitro.
|
Academic Article
|
Effects of sodium-potassium pump inhibition and low sodium on membrane potential in cultured embryonic chick heart cells.
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Academic Article
|
Hexakis(carbomethoxyisopropylisonitrile) technetium(I), a new myocardial perfusion imaging agent: binding characteristics in cultured chick heart cells.
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Academic Article
|
Na/H exchange in cultured chick heart cells. pHi regulation.
|
Academic Article
|
Expression of recombinant human multidrug resistance P-glycoprotein in insect cells confers decreased accumulation of technetium-99m-sestamibi.
|
Academic Article
|
Dynamic nature of the aortic regurgitant orifice area during diastole in patients with chronic aortic regurgitation.
|
Academic Article
|
Pharmacokinetic modeling of multidrug resistance P-glycoprotein transport of gamma-emitting substrates.
|
Academic Article
|
In vivo biochemistry, pharmacology, and physiology.
|
Academic Article
|
Multidrug resistance transporters and modulation.
|
Academic Article
|
Novel Tat-peptide chelates for direct transduction of technetium-99m and rhenium into human cells for imaging and radiotherapy.
|
Academic Article
|
Decreased hepatic accumulation and enhanced esterification of cholesterol in mice deficient in mdr1a and mdr1b P-glycoproteins.
|
Academic Article
|
Synthesis, characterization, and molecular structure of a gallium(III) complex of an amine-phenol ligand with activity against chloroquine-sensitive Plasmodium falciparum strains.
|
Academic Article
|
Transglutaminase 2 inhibitor, KCC009, disrupts fibronectin assembly in the extracellular matrix and sensitizes orthotopic glioblastomas to chemotherapy.
|
Academic Article
|
TAT-Bim induces extensive apoptosis in cancer cells.
|
Academic Article
|
Current state of imaging protein-protein interactions in vivo with genetically encoded reporters.
|
Academic Article
|
A method for quantification of nucleotides and nucleotide analogues in thymidine kinase assays using lanthanum phosphate coprecipitation.
|
Academic Article
|
Detection of protein-protein interactions in live cells and animals with split firefly luciferase protein fragment complementation.
|
Academic Article
|
Generation of a highly inducible Gal4-->Fluc universal reporter mouse for in vivo bioluminescence imaging.
|
Academic Article
|
Imaging spontaneous tumorigenesis: inflammation precedes development of peripheral NK tumors.
|
Academic Article
|
Loss of Par-1a/MARK3/C-TAK1 kinase leads to reduced adiposity, resistance to hepatic steatosis, and defective gluconeogenesis.
|
Academic Article
|
Dual-color click beetle luciferase heteroprotein fragment complementation assays.
|
Academic Article
|
Real-time imaging of notch activation with a luciferase complementation-based reporter.
|
Academic Article
|
Chromatin remodeling underlies the senescence-associated secretory phenotype of tumor stromal fibroblasts that supports cancer progression.
|
Academic Article
|
Interrogation of inhibitor of nuclear factor ?B a/nuclear factor ?B (I?Ba/NF-?B) negative feedback loop dynamics: from single cells to live animals in vivo.
|
Academic Article
|
Proteasome inhibitors evoke latent tumor suppression programs in pro-B MLL leukemias through MLL-AF4.
|
Academic Article
|
Electroneutral Na/H exchange may depolarize the membrane potential in steady state.
|
Academic Article
|
Interaction of (Na + K + 2 Cl) cotransport and the Na/K pump in cultured chick cardiac myocytes.
|
Academic Article
|
Na/H exchange in cultured chick heart cells: secondary stimulation of electrogenic transport during recovery from intracellular acidosis.
|
Academic Article
|
(Na + K + 2Cl) cotransport in cultured embryonic chick heart cells.
|
Academic Article
|
Physiologic criteria for electrogenic transport in tissue-cultured heart cells.
|
Academic Article
|
Multidrug resistance P-glycoprotein monoclonal antibody JSB-1 crossreacts with pyruvate carboxylase.
|
Academic Article
|
Effects of multidrug resistance (MDR1) P-glycoprotein expression levels and coordination metal on the cytotoxic potency of multidentate (N4O2) (ethylenediamine)bis[propyl(R-benzylimino)]metal(III) cations.
|
Academic Article
|
Novel technetium (III)-Q complexes for functional imaging of multidrug resistance (MDR1) P-glycoprotein.
|
Academic Article
|
Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal-fluid drug-permeability barrier.
|
Academic Article
|
Novel gallium(III) complexes transported by MDR1 P-glycoprotein: potential PET imaging agents for probing P-glycoprotein-mediated transport activity in vivo.
|
Academic Article
|
Quantitative analysis of permeation peptide complexes labeled with Technetium-99m: chiral and sequence-specific effects on net cell uptake.
|
Academic Article
|
Characterization of a novel 99mTc-carbonyl complex as a functional probe of MDR1 P-glycoprotein transport activity.
|
Academic Article
|
Recent advances in imaging the lungs of intact small animals.
|
Academic Article
|
Kinetics of regulated protein-protein interactions revealed with firefly luciferase complementation imaging in cells and living animals.
|
Academic Article
|
CXCR4 regulates growth of both primary and metastatic breast cancer.
|
Academic Article
|
Structure-activity relationships, kinetics, selectivity, and mechanistic studies of synthetic hydraphile channels in bacterial and mammalian cells.
|
Academic Article
|
Independent circadian oscillations of Period1 in specific brain areas in vivo and in vitro.
|
Academic Article
|
Selective cell uptake of modified Tat peptide-fluorophore conjugates in rat retina in ex vivo and in vivo models.
|
Academic Article
|
Linkage between cellular communications, energy utilization, and proliferation in metastatic neuroendocrine cancers.
|
Academic Article
|
Granulocyte colony-stimulating factor enhances bone tumor growth in mice in an osteoclast-dependent manner.
|
Academic Article
|
Blocking CXCR4-mediated cyclic AMP suppression inhibits brain tumor growth in vivo.
|
Academic Article
|
Bioluminescence imaging of period1 gene expression in utero.
|
Academic Article
|
Introduction to molecular imaging.
|
Academic Article
|
Intracellular water specific MR of microbead-adherent cells: HeLa cell intracellular water diffusion.
|
Academic Article
|
Identification of a ligand-induced transient refractory period in nuclear factor-kappaB signaling.
|
Academic Article
|
APT102, a novel adpase, cooperates with aspirin to disrupt bone metastasis in mice.
|
Academic Article
|
Quantitation of selective autophagic protein aggregate degradation in vitro and in vivo using luciferase reporters.
|
Academic Article
|
Rational design of novel red-shifted BRET pairs: Platforms for real-time single-chain protease biosensors.
|
Academic Article
|
Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease.
|
Academic Article
|
T-cell activation promotes tumorigenesis in inflammation-associated cancer.
|
Academic Article
|
Cyclic AMP suppression is sufficient to induce gliomagenesis in a mouse model of neurofibromatosis-1.
|
Academic Article
|
Flavokawain B, the hepatotoxic constituent from kava root, induces GSH-sensitive oxidative stress through modulation of IKK/NF-kappaB and MAPK signaling pathways.
|
Academic Article
|
Identification of FUSE-binding protein 1 as a regulatory mRNA-binding protein that represses nucleophosmin translation.
|
Academic Article
|
Cerenkov radiation energy transfer (CRET) imaging: a novel method for optical imaging of PET isotopes in biological systems.
|
Academic Article
|
Bioluminescence imaging captures the expression and dynamics of endogenous p21 promoter activity in living mice and intact cells.
|
Academic Article
|
Suppression of G-protein-coupled receptor kinase 3 expression is a feature of classical GBM that is required for maximal growth.
|
Academic Article
|
Mechanics of EGF receptor/ErbB2 kinase activation revealed by luciferase fragment complementation imaging.
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Academic Article
|
Imaging: strategies, controversies, and opportunities.
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Academic Article
|
On in vivo imaging in cancer.
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Academic Article
|
The epoxyketone-based proteasome inhibitors carfilzomib and orally bioavailable oprozomib have anti-resorptive and bone-anabolic activity in addition to anti-myeloma effects.
|
Academic Article
|
Antagonism of inhibitor of apoptosis proteins increases bone metastasis via unexpected osteoclast activation.
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Academic Article
|
F11R is a novel monocyte prognostic biomarker for malignant glioma.
|
Academic Article
|
Novel treatment option for MUC16-positive malignancies with the targeted TRAIL-based fusion protein Meso-TR3.
|
Academic Article
|
Prospective double-blinded comparison of MR imaging and aortography in the preoperative evaluation of abdominal aortic aneurysms.
|
Academic Article
|
Characterization of multidrug resistance P-glycoprotein transport function with an organotechnetium cation.
|
Academic Article
|
Prospective comparison of T2-weighted fast spin-echo, with and without fat suppression, and conventional spin-echo pulse sequences in the upper abdomen.
|
Academic Article
|
Membrane potential determination in large unilamellar vesicles with hexakis(2-methoxyisobutylisonitrile)technetium(I).
|
Academic Article
|
Modulation of the multidrug resistance P-glycoprotein: detection with technetium-99m-sestamibi in vivo.
|
Academic Article
|
Characterization of phosphine complexes of technetium(III) as transport substrates of the multidrug resistance P-glycoprotein and functional markers of P-glycoprotein at the blood-brain barrier.
|
Academic Article
|
A novel areneisonitrile Tc complex inhibits the transport activity of MDR P-glycoprotein.
|
Academic Article
|
Effects of cholesterol and enantiomeric cholesterol on P-glycoprotein localization and function in low-density membrane domains.
|
Academic Article
|
Imaging 26S proteasome activity and inhibition in living mice.
|
Academic Article
|
In vitro and in vivo characterization of a dual-function green fluorescent protein--HSV1-thymidine kinase reporter gene driven by the human elongation factor 1 alpha promoter.
|
Academic Article
|
Molecular imaging of host-pathogen interactions in intact small animals.
|
Academic Article
|
Characterization of coelenterazine analogs for measurements of Renilla luciferase activity in live cells and living animals.
|
Academic Article
|
Kinetics of in vivo elimination of suicide gene-expressing T cells affects engraftment, graft-versus-host disease, and graft-versus-leukemia after allogeneic bone marrow transplantation.
|
Academic Article
|
Characterization of a 67Ga/68Ga radiopharmaceutical for SPECT and PET of MDR1 P-glycoprotein transport activity in vivo: validation in multidrug-resistant tumors and at the blood-brain barrier.
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Academic Article
|
In vivo RNA interference-mediated ablation of MDR1 P-glycoprotein.
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Academic Article
|
Spectral unmixing of multicolored bioluminescence emitted from heterogeneous biological sources.
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Academic Article
|
TAT-BH4 and TAT-Bcl-xL peptides protect against sepsis-induced lymphocyte apoptosis in vivo.
|
Academic Article
|
Molecular imaging strategies for drug discovery and development.
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Academic Article
|
Single photon emission computed tomography and positron emission tomography imaging of multi-drug resistant P-glycoprotein--monitoring a transport activity important in cancer, blood-brain barrier function and Alzheimer's disease.
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Academic Article
|
Second-generation triple reporter for bioluminescence, micro-positron emission tomography, and fluorescence imaging.
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Academic Article
|
Optical imaging of bacterial infection in living mice using a fluorescent near-infrared molecular probe.
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Academic Article
|
Biochemical and in vivo characterization of a small, membrane-permeant, caspase-activatable far-red fluorescent peptide for imaging apoptosis.
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Academic Article
|
Continuous delivery of D-luciferin by implanted micro-osmotic pumps enables true real-time bioluminescence imaging of luciferase activity in vivo.
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Academic Article
|
Disruption of CXCR4 enhances osteoclastogenesis and tumor growth in bone.
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Academic Article
|
Factors affecting human T cell engraftment, trafficking, and associated xenogeneic graft-vs-host disease in NOD/SCID beta2mnull mice.
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Academic Article
|
Real-time imaging of beta-catenin dynamics in cells and living mice.
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Academic Article
|
Noninvasive optical imaging of staphylococcus aureus bacterial infection in living mice using a Bis-dipicolylamine-Zinc(II) affinity group conjugated to a near-infrared fluorophore.
|
Academic Article
|
Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100.
|
Academic Article
|
Luciferase fragment complementation imaging of conformational changes in the epidermal growth factor receptor.
|
Academic Article
|
Proteasome inhibition blocks ligand-induced dynamic processing and internalization of epidermal growth factor receptor via altered receptor ubiquitination and phosphorylation.
|
Academic Article
|
Bioluminescence imaging of myeloperoxidase activity in vivo.
|
Academic Article
|
Revascularization of ischemic limbs after transplantation of human bone marrow cells with high aldehyde dehydrogenase activity.
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Academic Article
|
The bisphosphonate zoledronic acid decreases tumor growth in bone in mice with defective osteoclasts.
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Academic Article
|
Immunodeficient mouse strains display marked variability in growth of human melanoma lung metastases.
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Academic Article
|
LRP6 overexpression defines a class of breast cancer subtype and is a target for therapy.
|
Academic Article
|
In vivo administration of hypomethylating agents mitigate graft-versus-host disease without sacrificing graft-versus-leukemia.
|
Academic Article
|
Strain-specific susceptibility for pulmonary metastasis of sarcoma 180 cells in inbred mice.
|
Academic Article
|
CXCL12 alone is insufficient for gliomagenesis in Nf1 mutant mice.
|
Academic Article
|
In vivo cell death mediated by synthetic ion channels.
|
Academic Article
|
Nano in cancer: linking chemistry, biology, and clinical applications in vivo.
|
Academic Article
|
Bioluminescent imaging reveals divergent viral pathogenesis in two strains of Stat1-deficient mice, and in a?? interferon receptor-deficient mice.
|
Academic Article
|
A bioluminescent transposon reporter-trap identifies tumor-specific microenvironment-induced promoters in Salmonella for conditional bacterial-based tumor therapy.
|
Academic Article
|
Quantitation of the effect of ErbB2 on epidermal growth factor receptor binding and dimerization.
|
Academic Article
|
Caspase-activated cell-penetrating peptides reveal temporal coupling between endosomal release and apoptosis in an RGC-5 cell model.
|
Academic Article
|
IFN?R signaling mediates alloreactive T-cell trafficking and GVHD.
|
Academic Article
|
The ADP receptor P2RY12 regulates osteoclast function and pathologic bone remodeling.
|
Academic Article
|
The collagen receptor discoidin domain receptor 2 stabilizes SNAIL1 to facilitate breast cancer metastasis.
|
Academic Article
|
Forkhead box O1 (FOXO1) protein, but not p53, contributes to robust induction of p21 expression in fasted mice.
|
Academic Article
|
Conjugation to a SMAC mimetic potentiates sigma-2 ligand induced tumor cell death in ovarian cancer.
|
Academic Article
|
Contribution of p53 to metastasis.
|
Academic Article
|
Theoretical effects of transmembrane electroneutral exchange on membrane potential.
|
Academic Article
|
MDR1 gene-specific monoclonal antibody C494 cross-reacts with pyruvate carboxylase.
|
Academic Article
|
Novel hexakis(areneisonitrile)technetium(I) complexes as radioligands targeted to the multidrug resistance P-glycoprotein.
|
Academic Article
|
Functional imaging of multidrug-resistant P-glycoprotein with an organotechnetium complex.
|
Academic Article
|
Characterization of functional assays of multidrug resistance P-glycoprotein transport activity.
|
Academic Article
|
Characterization of drug specificity by pharmacokinetic analysis in gene knockout mice.
|
Academic Article
|
Effects of MDR1 and MDR3 P-glycoproteins, MRP1, and BCRP/MXR/ABCP on the transport of (99m)Tc-tetrofosmin.
|
Academic Article
|
Synthesis and characterization of a Gd-DOTA-D-permeation peptide for magnetic resonance relaxation enhancement of intracellular targets.
|
Academic Article
|
Imaging multidrug resistance P-glycoprotein transport function using microPET with technetium-94m-sestamibi.
|
Academic Article
|
Real-time imaging of ligand-induced IKK activation in intact cells and in living mice.
|
Academic Article
|
Monitoring proteasome activity in cellulo and in living animals by bioluminescent imaging: technical considerations for design and use of genetically encoded reporters.
|
Academic Article
|
Intracellular water-specific MR of microbead-adherent cells: the HeLa cell intracellular water exchange lifetime.
|
Academic Article
|
PET imaging of heat-inducible suicide gene expression in mice bearing head and neck squamous cell carcinoma xenografts.
|
Academic Article
|
Advances in bioluminescence imaging of live animal models.
|
Academic Article
|
Measuring brain tumor growth: combined bioluminescence imaging-magnetic resonance imaging strategy.
|
Academic Article
|
Human cord blood progenitors with high aldehyde dehydrogenase activity improve vascular density in a model of acute myocardial infarction.
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Academic Article
|
Asp-960/Glu-961 controls the movement of the C-terminal tail of the epidermal growth factor receptor to regulate asymmetric dimer formation.
|
Academic Article
|
Monitoring molecular-specific pharmacodynamics of rapamycin in vivo with inducible Gal4->Fluc transgenic reporter mice.
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Academic Article
|
The ARF tumor suppressor regulates bone remodeling and osteosarcoma development in mice.
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Academic Article
|
Knocking down nucleolin expression in gliomas inhibits tumor growth and induces cell cycle arrest.
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Academic Article
|
Breast cancer cell targeting by prenylation inhibitors elucidated in living animals with a bioluminescence reporter.
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Academic Article
|
Dynamic analysis of the epidermal growth factor (EGF) receptor-ErbB2-ErbB3 protein network by luciferase fragment complementation imaging.
|
Academic Article
|
Intracellular pH regulation in cultured embryonic chick heart cells. Na(+)-dependent Cl-/HCO3- exchange.
|
Academic Article
|
Aortic flow velocity patterns in chronic aortic regurgitation: implications for Doppler echocardiography.
|
Academic Article
|
Probing the chloroquine resistance locus of Plasmodium falciparum with a novel class of multidentate metal(III) coordination complexes.
|
Academic Article
|
Multidrug resistance (MDR1) P-glycoprotein enhances esterification of plasma membrane cholesterol.
|
Academic Article
|
Imaging reversal of multidrug resistance in living mice with bioluminescence: MDR1 P-glycoprotein transports coelenterazine.
|
Academic Article
|
Optimizing luciferase protein fragment complementation for bioluminescent imaging of protein-protein interactions in live cells and animals.
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Academic Article
|
Imaging protein-protein interactions in whole cells and living animals.
|
Academic Article
|
Targeted inhibition of cyclic AMP phosphodiesterase-4 promotes brain tumor regression.
|
Academic Article
|
Stably integrated luxCDABE for assessment of Salmonella invasion kinetics.
|
Academic Article
|
CD47 regulates bone mass and tumor metastasis to bone.
|
Academic Article
|
An anti-apoptotic peptide improves survival in lethal total body irradiation.
|
Academic Article
|
An improved cell-penetrating, caspase-activatable, near-infrared fluorescent peptide for apoptosis imaging.
|
Academic Article
|
Dissection of platelet and myeloid cell defects by conditional targeting of the beta3-integrin subunit.
|
Academic Article
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A pharmacologic inhibitor of the protease Taspase1 effectively inhibits breast and brain tumor growth.
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CXCL12 mediates trophic interactions between endothelial and tumor cells in glioblastoma.
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18F-AFETP, 18F-FET, and 18F-FDG imaging of mouse DBT gliomas.
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P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model.
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CD8+ T cells regulate bone tumor burden independent of osteoclast resorption.
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Evaluating new therapies in gastrointestinal stromal tumor using in vivo molecular optical imaging.
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Combined VEGF and CXCR4 antagonism targets the GBM stem cell population and synergistically improves survival in an intracranial mouse model of glioblastoma.
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DAPK3 suppresses acini morphogenesis and is required for mouse development.
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Type I interferons link viral infection to enhanced epithelial turnover and repair.
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A rapid bioluminescence assay for measuring myeloperoxidase activity in human plasma.
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Glypican-1 identifies cancer exosomes and detects early pancreatic cancer.
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Novel chemical library screen identifies naturally occurring plant products that specifically disrupt glioblastoma-endothelial cell interactions.
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Fasting protects mice from lethal DNA damage by promoting small intestinal epithelial stem cell survival.
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Radiomics and Radiogenomics in Breast Cancer
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A rapid bioluminescence assay for measuring myeloperoxidase activity in human plasma
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p53 deficiency linked to B cell translocation gene 2 (BTG2) loss enhances metastatic potential by promoting tumor growth in primary and metastatic sites in patient-derived xenograft (PDX) models of triple-negative breast cancer
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The IL-15-Based ALT-803 Complex Enhances FcγRIIIa-Triggered NK Cell Responses and in Vivo Clearance of B Cell Lymphomas
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Gallium(III) Schiff-base complexes as potential PET agents for evaluation of multidrug resistance (MDR1) P-glycoprotein transport activity
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Bioluminescence imaging of prenylation inhibition - Response
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Simultaneous inhibition of hedgehog signaling and tumor proliferation remodels stroma and enhances pancreatic cancer therapy.
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Vascular Endothelial Growth Factor Receptor-1 Is Synthetic Lethal to Aberrant {beta}-Catenin Activation in Colon Cancer.
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The IL-15-Based ALT-803 Complex Enhances Fc?RIIIa-Triggered NK Cell Responses and In Vivo Clearance of B Cell Lymphomas.
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p53 deficiency linked to B cell translocation gene 2 (BTG2) loss enhances metastatic potential by promoting tumor growth in primary and metastatic sites in patient-derived xenograft (PDX) models of triple-negative breast cancer.
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Automated, Resin-Based Method to Enhance the Specific Activity of Fluorine-18 Clicked PET Radiotracers.
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p38 MAPK inhibits nonsense-mediated RNA decay in response to persistent DNA damage in noncycling cells.
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Nucleoside Diphosphate Kinase-3 (NME3) Enhances TLR5-Induced NF?B Activation.
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Androgen Receptor Signaling in Castration-Resistant Prostate Cancer Alters Hyperpolarized Pyruvate to Lactate Conversion and Lactate Levels In Vivo.
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A Coclinical Radiogenomic Validation Study: Conserved Magnetic Resonance Radiomic Appearance of Periostin-Expressing Glioblastoma in Patients and Xenograft Models.
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Caspase-3 Substrates for Noninvasive Pharmacodynamic Imaging of Apoptosis by PET/CT.
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Development of a Potential Gallium-68-Labelled Radiotracer Based on DOTA-Curcumin for Colon-Rectal Carcinoma: From Synthesis to In Vivo Studies.
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Multiwalled Carbon Nanotubes for Combination Therapy: a Biodistribution and Efficacy Pilot Study.
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Bortezomib
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Forkhead Box Protein O1
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Concept
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Glycogen Synthase Kinase 3 beta
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Concept
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NF-KappaB Inhibitor alpha
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Concept
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Bcl-2-Like Protein 11
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rhoC GTP-Binding Protein
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B7 Antigens
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B7-H1 Antigen
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Triple Negative Breast Neoplasms
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Combining Hyperpolarized Real-Time Metabolic Imaging and NMR Spectroscopy To Identify Metabolic Biomarkers in Pancreatic Cancer.
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Assessing Metabolic Intervention with a Glutaminase Inhibitor in Real-Time by Hyperpolarized Magnetic Resonance in Acute Myeloid Leukemia.
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A Novel Mitochondrial Inhibitor Blocks MAPK Pathway and Overcomes MAPK Inhibitor Resistance in Melanoma.
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Novel derivatives of anaplastic lymphoma kinase inhibitors: Synthesis, radiolabeling, and preliminary biological studies of fluoroethyl analogues of crizotinib, alectinib, and ceritinib.
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Mechanism-Specific Pharmacodynamics of a Novel Complex-I Inhibitor Quantified by Imaging Reversal of Consumptive Hypoxia with [18F]FAZA PET In Vivo.
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Induction of antitumor immunity in mice by the combination of nanoparticle-based photothermolysis and anti-PD-1 checkpoint inhibition.
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18F-fluorodeoxyglucose positron emission tomography correlates with tumor immunometabolic phenotypes in resected lung cancer.
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Analysis of RAS protein interactions in living cells reveals a mechanism for pan-RAS depletion by membrane-targeted RAS binders.
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Axonal Transport as an In Vivo Biomarker for Retinal Neuropathy.
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Mistiming Death: Modeling the Time-Domain Variability of Tumor Apoptosis and Implications for Molecular Imaging of Cell Death.
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Streamlining the Quantitative Metrics Workflow at a Comprehensive Cancer Center.
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Myeloid cell-derived HOCl is a paracrine effector that trans-inhibits IKK/NF-?B in melanoma cells and limits early tumor progression.
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A Reversible Shift of Driver Dependence from EGFR to Notch1 in Non-Small Cell Lung Cancer as a Cause of Resistance to Tyrosine Kinase Inhibitors.
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Excess exogenous pyruvate inhibits lactate dehydrogenase activity in live cells in an MCT1-dependent manner.
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Measuring the Metabolic Evolution of Glioblastoma throughout Tumor Development, Regression, and Recurrence with Hyperpolarized Magnetic Resonance.
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RAS-Driven Macropinocytosis of Albumin or Dextran Reveals Mutation-Specific Target Engagement of RAS p.G12C Inhibitor ARS-1620 by NIR-Fluorescence Imaging.
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Imaging of innate immunity activation in vivo with a redox-tuned PET reporter.
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PET/MR Imaging of a Lung Metastasis Model of Clear Cell Renal Cell Carcinoma with (2S,4R)-4-[18F]Fluoroglutamine.
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Metabolic requirement for GOT2 in pancreatic cancer depends on environmental context.
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Apoptosis Detection in Retinal Ganglion Cells Using Quantitative Changes in Multichannel Fluorescence Colocalization.
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TLR5 agonists enhance anti-tumor immunity and overcome resistance to immune checkpoint therapy.
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Inhibition of myeloperoxidase enhances immune checkpoint therapy for melanoma.
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Gender Differences in a Mouse Model of Hepatocellular Carcinoma Revealed Using Multi-Modal Imaging.
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Production, isolation, and shipment of clinically relevant quantities of astatine-211: A simple and efficient approach to increasing supply.
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Dimerization of the 4Ig isoform of B7-H3 in tumor cells mediates enhanced proliferation and tumorigenic signaling.
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